SERS encoded nanoparticles

Surface Plasmon Resonance and Raman Spectroscopy

Metallic nanoparticles can be used to enhance Raman spectroscopy. Their special properties related to their size and shape have proven to enhance this optical technique.

It is well-known that nanoparticles can be functionalized with a wide range of molecules or biomolecules. The Raman unique fingerprint intensity of this molecules is largely enhanced due to the localized surface plasmon resonance (LSPR) of the metallic particles, achieving highly sensible tags or markers, the so-called Raman reporters or Raman labels. The use of this structured nanomaterial can be employed for the development of highly sensitive (bio)sensing devices, or as targets in many biological applications.

Compared to fluorophores or dyes, they exhibit excellent photostability and narrower bands. Actually, spectra from the different compounds can be clearly distinguished, since Raman spectroscopy provides a unique molecular fingerprint.

Characteristics of  SERS encoded nanoparticles

• Quasi-spherical nanoparticles
• High Raman cross-section
• High colloidal stability
• Improved biocompatibility